SnapGene " acgcgtgtagtcttatgcaatactcttgtagtcttgcaacatggtaacgatgagttagcaacatgccttacaaggagagaaaaagcaccgtgcatgccgattggtggaagtaaggtggtacgatcgtgccttattaggaaggcaacagacgggtctgacatggattggacgaaccactgaattgccgcattgcagagatattgtatttaagtgcctagctcgatacaataaacgggtctctctggttagaccagatctgagcctgggagctctctggctaactagggaacccactgcttaagcctcaataaagcttgccttgagtgcttcaagtagtgtgtgcccgtctgttgtgtgactctggtaactagagatccctcagacccttttagtcagtgtggaaaatctctagcagtggcgcccgaacagggacctgaaagcgaaagggaaaccagagctctctcgacgcaggactcggcttgctgaagcgcgcacggcaagaggcgaggggcggcgactggtgagtacgccaaaaattttgactagcggaggctagaaggagagagatgggtgcgagagcgtcagtattaagcgggggagaattagatcgcgatgggaaaaaattcggttaaggccagggggaaagaaaaaatataaattaaaacatatagtatgggcaagcagggagctagaacgattcgcagttaatcctggcctgttagaaacatcagaaggctgtagacaaatactgggacagctacaaccatcccttcagacaggatcagaagaacttagatcattatataatacagtagcaaccctctattgtgtgcatcaaaggatagagataaaagacaccaaggaagctttagacaagatagaggaagagcaaaacaaaagtaagaccaccgcacagcaagcggccactgatcttcagacctggaggaggagatatgagggacaattggagaagtgaattatataaatataaagtagtaaaaattgaaccattaggagtagcacccaccaaggcaaagagaagagtggtgcagagagaaaaaagagcagtgggaataggagctttgttccttgggttcttgggagcagcaggaagcactatgggcgcagcctcaatgacgctgacggtacaggccagacaattattgtctggtatagtgcagcagcagaacaatttgctgagggctattgaggcgcaacagcatctgttgcaactcacagtctggggcatcaagcagctccaggcaagaatcctggctgtggaaagatacctaaaggatcaacagctcctggggatttggggttgctctggaaaactcatttgcaccactgctgtgccttggaatgctagttggagtaataaatctctggaacagattggaatcacacgacctggatggagtgggacagagaaattaacaattacacaagcttaatacactccttaattgaagaatcgcaaaaccagcaagaaaagaatgaacaagaattattggaattagataaatgggcaagtttgtggaattggtttaacataacaaattggctgtggtatataaaattattcataatgatagtaggaggcttggtaggtttaagaatagtttttgctgtactttctatagtgaatagagttaggcagggatattcaccattatcgtttcagacccacctcccaaccccgaggggacccgacaggcccgaaggaatagaagaagaaggtggagagagagacagagacagatccattcgattagtgaacggatctcgacggtATCGGTtaacttttaaaagaaaaggggggattggggggtacagtgcaggggaaagaatagtagacataatagcaacagacatacaaactaaagaattacaaaaacaaattacaaaaattcaaaattttatcgatactagtattatgcccagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcggtttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccattgacgcaaatgggcggtaggcgtgtacggtgggaggtTtatataagcagagctcgtttagtgaaccgtcagatcgcctggagacgccatccacgctgttttgacctccatagaagattctagagctagcCTGATACGAACTCGgaattcGCCACCatgcagccctcactagccccgtgcctcatctgcctacttgtgcacgctgccttctgtgctgtggagggccaggggtggcaagccttcaggaatgatgccacagaggtcatcccagggcttggagagtaccccgagcctcctcctgagaacaaccagaccatgaaccgggcggagaatggaggcagacctccccaccatccctatgacgccaaagatgtgtccgagtacagctgccgcgagctgcactacacccgcttcctgacagacggcccatgccgcagcgccaagccggtcaccgagttggtgtgctccggccagtgcggccccgcgcggctgctgcccaacgccatcgggcgcgtgaagtggtggcgcccgaacggaccggatttccgctgcatcccggatcgctaccgcgcgcagcgggtgcagctgctgtgccccgggggcgcggcgccgcgctcgcgcaaggtgcgtctggtggcctcgtgcaagtgcaagcgcctcacccgcttccacaaccagtcggagctcaaggacttcgggccggagaccgcgcggccgcagaagggtcgcaagccgcggcccggcgcccggggagccaaagccaaccaggcggagctggagaacgcctacCTCGAGTACCCATACGACGTACCTGATTATGCAACTTATCCTTATGATGTACCTGATTATGCTAGCTATCCTTATGATGTCCCAGACTACGCATAGggatccCTGCGATATCCAGCgcggccgcGaaggatctgcgatcgctccggtgcccgtcagtgggcagagcgcacatcgcccacagtccccgagaagttggggggaggggtcggcaattgaacgggtgcctagagaaggtggcgcggggtaaactgggaaagtgatgtcgtgtactggctccgcctttttcccgagggtgggggagaaccgtatataagtgcagtagtcgccgtgaacgttctttttcgcaacgggtttgccgccagaacacagctgaagcttcgaggggctcgcatctctccttcacgcgcccgccgccctacctgaggccgccatccacgccggttgagtcgcgttctgccgcctcccgcctgtggtgcctcctgaactgcgtccgccgtctaggtaagtttaaagctcaggtcgagaccgggcctttgtccggcgctcccttggagcctacctagactcagccggctctccacgctttgcctgaccctgcttgctcaactctacgtctttgtttcgttttctgttctgcgccgttacagatccaagctgtgaccggcgcctacgctagacgccaccatggagagcgacgagagcggcctgcccgccatggagatcgagtgccgcatcaccggcaccctgaacggcgtggagttcgagctggtgggcggcggagagggcacccccaagcagggccgcatgaccaacaagatgaagagcaccaaaggcgccctgaccttcagcccctacctgctgagccacgtgatgggctacggcttctaccacttcggcacctaccccagcggctacgagaaccccttcctgcacgccatcaacaacggcggctacaccaacacccgcatcgagaagtacgaggacggcggcgtgctgcacgtgagcttcagctaccgctacgaggccggccgcgtgatcggcgacttcaaggtggtgggcaccggcttccccgaggacagcgtgatcttcaccgacaagatcatccgcagcaacgccaccgtggagcacctgcaccccatgggcgataacgtgctggtgggcagcttcgcccgcaccttcagcctgcgcgacggcggctactacagcttcgtggtggacagccacatgcacttcaagagcgccatccaccccagcatcctgcagaacgggggccccatgttcgccttccgccgcgtggaggagctgcacagcaacaccgagctgggcatcgtggagtaccagcacgccttcaagacccccatcgccttcgccagatcccgcgctcagtcgtccaattctgccgtggacggcaccgccggacccggctccaccggatctcgcgagggcagaggaagtcttctaacatgcggtgacgtggaggagaatcccggccctatgaccgagtacaagcccacggtgcgcctcgccacccgcgacgacgtccccagggccgtacgcaccctcgccgccgcgttcgccgactaccccgccacgcgccacaccgtcgatccggaccgccacatcgagcgggtcaccgagctgcaagaactcttcctcacgcgcgtcgggctcgacatcggcaaggtgtgggtcgcggacgacggcgccgcggtggcggtctggaccacgccggagagcgtcgaagcgggggcggtgttcgccgagatcggcccgcgcatggccgagttgagcggttcccggctggccgcgcagcaacagatggaaggcctcctggcgccgcaccggcccaaggagcccgcgtggttcctggccaccgtcggcgtctcgcccgaccaccagggcaagggtctgggcagcgccgtcgtgctccccggagtggaggcggccgagcgcgccggggtgcccgccttcctggagacctccgcgccccgcaacctccccttctacgagcggctcggcttcaccgtcaccgccgacgtcgaggtgcccgaaggaccgcgcacctggtgcatgacccgcaagcccggtgcctgaaatcaacctctggattacaaaatttgtgaaagattgactggtattcttaactatgttgctccttttacgctatgtggatacgctgctttaatgcctttgtatcatgctattgcttcccgtatggctttcattttctcctccttgtataaatcctggttgctgtctctttatgaggagttgtggcccgttgtcaggcaacgtggcgtggtgtgcactgtgtttgctgacgcaacccccactggttggggcattgccaccacctgtcagctcctttccgggactttcgctttccccctccctattgccacggcggaactcatcgccgcctgccttgcccgctgctggacaggggctcggctgttgggcactgacaattccgtggtgttgtcggggaagctgacgtcctttccatggctgctcgcctgtgttgccacctggattctgcgcgggacgtccttctgctacgtcccttcggccctcaatccagcggaccttccttcccgcggcctgctgccggctctgcggcctcttccgcgtctccgccttcgccctcagacgagtcggatctccctttggccgcctccccgcctggtacctttaagaccaatgacttacaaggcagctgtagatcttagccactttttaaaagaaaaggggggactggaagggctaattcactcccaacgaaaataagatctgctttttgcttgtactgggtctctctggttagaccagatctgagcctgggagctctctggctaactagggaacccactgcttaagcctcaataaagcttgccttgagtgcttcaagtagtgtgtgcccgtctgttgtgtgactctggtaactagagatccctcagacccttttagtcagtgtggaaaatctctagcagtagtagttcatgtcatcttattattcagtatttataacttgcaaagaaatgaatatcagagagtgagaggaacttgtttattgcagcttataatggttacaaataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgcattctagttgtggtttgtccaaactcatcaatgtatcttatcatgtctggctctagctatcccgcccctaactccgcccagttccgcccattctccgccccatggctgactaattttttttatttatgcagaggccgaggccgcctcggcctctgagctattccagaagtagtgaggaggcttttttggaggcctagacttttgcagagacggcccaaattcgtaatcatggtcatagctgtttcctgtgtgaaattgttatccgctcacaattccacacaacatacgagccggaagcataaagtgtaaagcctggggtgcctaatgagtgagctaactcacattaattgcgttgcgctcactgcccgctttccagtcgggaaacctgtcgtgccagctgcattaatgaatcggccaacgcgcggggagaggcggtttgcgtattgggcgctcttccgcttcctcgctcactgactcgctgcgctcggtcgttcggctgcggcgagcggtatcagctcactcaaaggcggtaatacggttatccacagaatcaggggataacgcaggaaagaacatgtgagcaaaaggccagcaaaaggccaggaaccgtaaaaaggccgcgttgctggcgtttttccataggctccgcccccctgacgagcatcacaaaaatcgacgctcaagtcagaggtggcgaaacccgacaggactataaagataccaggcgtttccccctggaagctccctcgtgcgctctcctgttccgaccctgccgcttaccggatacctgtccgcctttctcccttcgggaagcgtggcgctttctcatagctcacgctgtaggtatctcagttcggtgtaggtcgttcgctccaagctgggctgtgtgcacgaaccccccgttcagcccgaccgctgcgccttatccggtaactatcgtcttgagtccaacccggtaagacacgacttatcgccactggcagcagccactggtaacaggattagcagagcgaggtatgtaggcggtgctacagagttcttgaagtggtggcctaactacggctacactagaaggacagtatttggtatctgcgctctgctgaagccagttaccttcggaaaaagagttggtagctcttgatccggcaaacaaaccaccgctggtagcggtggtttttttgtttgcaagcagcagattacgcgcagaaaaaaaggatctcaagaagatcctttgatcttttctacggggtctgacgctcagtggaacgaaaactcacgttaagggattttggtcatgagattatcaaaaaggatcttcacctagatccttttaaattaaaaatgaagttttaaatcaatctaaagtatatatgagtaaacttggtctgacagttaccaatgcttaatcagtgaggcacctatctcagcgatctgtctatttcgttcatccatagttgcctgactccccgtcgtgtagataactacgatacgggagggcttaccatctggccccagtgctgcaatgataccgcgagacccacgctcaccggctccagatttatcagcaataaaccagccagccggaagggccgagcgcagaagtggtcctgcaactttatccgcctccatccagtctattaattgttgccgggaagctagagtaagtagttcgccagttaatagtttgcgcaacgttgttgccattgctacaggcatcgtggtgtcacgctcgtcgtttggtatggcttcattcagctccggttcccaacgatcaaggcgagttacatgatcccccatgttgtgcaaaaaagcggttagctccttcggtcctccgatcgttgtcagaagtaagttggccgcagtgttatcactcatggttatggcagcactgcataattctcttactgtcatgccatccgtaagatgcttttctgtgactggtgagtactcaaccaagtcattctgagaatagtgtatgcggcgaccgagttgctcttgcccggcgtcaatacgggataataccgcgccacatagcagaactttaaaagtgctcatcattggaaaacgttcttcggggcgaaaactctcaaggatcttaccgctgttgagatccagttcgatgtaacccactcgtgcacccaactgatcttcagcatcttttactttcaccagcgtttctgggtgagcaaaaacaggaaggcaaaatgccgcaaaaaagggaataagggcgacacggaaatgttgaatactcatactcttcctttttcaatattattgaagcatttatcagggttattgtctcatgagcggatacatatttgaatgtatttagaaaaataaacaaataggggttccgcgcacatttccccgaaaagtgccacctgacgtctaagaaaccattattatcatgacattaacctataaaaataggcgtatcacgaggccctttcgtctcgcgcgtttcggtgatgacggtgaaaacctctgacacatgcagctcccggagacggtcacagcttgtctgtaagcggatgccgggagcagacaagcccgtcagggcgcgtcagcgggtgttggcgggtgtcggggctggcttaactatgcggcatcagagcagattgtactgagagtgcaccatatgcggtgtgaaataccgcacagatgcgtaaggagaaaataccgcatcaggcgccattcgccattcaggctgcgcaactgttgggaagggcgatcggtgcgggcctcttcgctattacgccagctggcgaaagggggatgtgctgcaaggcgattaagttgggtaacgccagggttttcccagtcacgacgttgtaaaacgacggccagtgccaagctg K 1 . . 8 . 2 : % , 3 * 5 " 1 / ( ! + $ $ 5 3 # 7 ; 5 4 $ : ) 4 6 4 < 2 * ' + 1 7 ' $ ( $ $ / 6 / + + / K ) # % " ! ! % " % ! % ' $ ' ( " $ * / . & $ ) , + 3 # ! $ & ( ! 1 " " ! & & * " , ! $ ' $ $ ? ) " 3 ) ) R " 6 # 7 / & ( ! ) 6 8 & # 3
) 1 * & . + Q , % / 4 1 ' 8 % - 1 QR}~ %!"#0S
\ G H I N u
wxVW)8@ABr !"". Sf-K {11M] J 9rCEs < t !k"" 8C&$T
B O _ v *} N !!"". `{M ~ k
( "
y'X M: | !!p"}"8 I #.T4L[=2J - ^ r x K
3QxHKG:`zt !!8". i g]r.U0Oku2d .:I#wF %( = ] u l"
G |
g !" N
! YC
#=
sD2 f q 9U :
x
` m \
@@o2\+/|"[ ^ O k!t!!! "x" * t jx E%w y
k 4 U " rD'I <
M|^ " t .
C P
8~( 1 !: a| l
{
U o p
s6]`,*5Y|y> } H!!!J"q"""% w>X # T g (t C P z $ a !, &@ W
9/`e-ON2}L; !!\"3 x~N
D
M
) 8 P ,
CzUlw hOU^g 2 T!~""* $p>K r L
*
W%,I}^uMSx{wzN R!5 J L r/13>UL . y ? h
4=RNLHf;msu w ! "9"" 3 A
\q3 5
@
Xya{aoz/ ' E a "1
@v&5M _ s '
6?nXJ \e
] R !!/ j +^sVs
? A j P/Q;Jp
> ^ m"( N h 13 ;`$`G) !#!w!"";"" W/PvPl7] e Neby v ! l
{ [ f
osx&G 0 5ci M n!!/"" HNl6} b q
hu ""+ y t]
T h&h> _ + t"$ ou(r
(:Z)C$'wAtZm !q!!"" Ug?N
D $6 4!!! d O"
E6 Z $ }
0
]>= Y 5 g r + H V v
y
n Z
v>AF3fz-!}\ bjq
lAqv L X _ P l!u! " OQ`; ;
]0[ #? ~ !! "3 Y } CS:=H+ 3 C =
I
a ]
Zcp,QA !"y""" L+:F< #25s%5 V K + m k^_x z
+l) G I !4""" H! )BN K! u y^& Scxc "# ](X7
D =
}Ncm2]*81 x 6 h k !h""" 5 ss : V JU59 ~
~}A_ g
] H f!" <E G
{_8 ,Pm N
\ D Q B
Nz5BN) ! D+u /
np>v = o !!!" Y
t
29Tu 2 d + !]!! 9 m
Dw| 7 !O } K
U
6 N p s A7^->!06TZ^ppzY !!!!"{" <a
8'#] ~ r""" Bo
E
k
taL}(6? F I!d!!2"; b$
S
m
|
4 V ) q
%Zr+q "$Dn-n` { a b!!K"`"5 (ORdx- !
< $ p) /Jo r }
% !! "4 # 9 .xHuY
G U Ku[D k c T b l b"" [ ?
_IisZ_{ - 3 !D"$ T Y=?5 + h&hO CQ ( ! !"*": rE[9 E X
[
u eQ>P 3W;7<] R !]"""" 'T
$:v|0 OgA t ") '8Ea7A
p9f".mt~:C P !!4 +?
aS/Mp 0 8 !6 _
+
* 9 K
-
9
L
q
\
-Dcx &tPV3 9
i !4 y O l &
E
e
a g 0
+L*H\y`-Sh! R n B !M"T"""""< @ -<gJ" + < ]
c O
V
_
D!t2WY_
b{ "2 Uj
N
^
~
Q X 2
!
H{Vim.Fi
+6RU U!!* |z/L R } A M
&?L s { !o"""' H - F\q3T
<c X-J_vy$ \ 7" p Hs
l x
~{'+ %w}?v n +
sNT|x 1KO y ` G!S!I"[""1 K q02?Kou %pq & g 5>W+IlntLvy. D !
"7 M *V
O6\ > z @ i OrM:_o x "!:"' s4\Mkp
Sg%gt L "."$ |Tf>M
/
'< !!( BN*i*H
u
Y pu K } !""$ l K G*]9; Rb14Mr ( F J b 4 WTr46
C }
z|b7 0 9 w M U \ " 8 A
1Au{* n "$ AN#
( 7@YKS!]X \ E !!/ 8 S -w'NQXGh.^n q ' 2 S !!6 7`6
t
ou8= fV67 @ !!"" ,f \ *
J ` f
Gh, T !/ G o ,vE[
@ k >K 0 _ r z 6"n"""+ Sjt
$N5[ V
9f^- K !! k Jt
B |
Q0qt
I m !"+ R +6M_W[ )
I e
gR<5 m ? !!"/ Q 5DR # 4Z d
8=] /, q !"K O P ijkQz !"2'deqryDW7<a% -.fg* + V W d n o p
!A!B!x!<"") lc(jszEXwFb&ah e C!#"=" {3Ufz HF J + X $!y!" lQ3.Yxf b_ @ f # 2%0`Qm8Dcf Y z w D!$">"% Xm)^kt{ W 'R:$ 2 1 dwFOG'ci G - Jb
| \ p3tw]k e "" % ; |m
Jga 0B9G Y " m4Vd { g
Vyn , ' !d" 0 j MI'HK i %!:!z! ( 6d^/y 1Ou+M0 " 1 m4g [\c` % 2!o! Z < " > ] R j
M<
HA @ N g !!!"0" Im17Rgn9E Iu Z { E!! 3#Oa%1B DdT / x ?! !#~ g! # " &Q %"?"! c 8r %oX %3 q "% JY *_l F!\v / )!,!7!"" !9|
4P;D h ! n-u (iSI$j 2 r P"W" z ^h
/ UKidjr} u"" AxGa-ia H /!M!!F" e'
'i(A
W ` , 5 % ux
3
_kPH g? q & E ! v K
] q4[*um( r!!" . w } ;U%Z^[E P!"" )
j DxxBu f !"% ps7 c
}
7
")(Bln
y ""' ({n(Ko
6 6E 7 w Z !,"$ E h}Sbhob 1e%dH ! & < @O- K:
!5!! V{
=C ! $B| h
!Fz3* : [ ( "e" n [W
37o ! ` P/ # Q0Wz- < e5e
W e ' V 2
1
dy^kq(ZO '"A"( X?A k .??
L = j B &!"" &
>NcJ" S !;!{!$ ~1
j
Ec|I # * 7e,BJ_ $ 0z! F ~ |9M j""/ h /NZjtI w
2PwBG<9 fH" . ) e s i D9
w
[
?L. 3 T ] 0
] & =W z
o 4v,g{N1=~ # !!" 2 @ )
?
m]rdw y & M ` v Q " k r
Z e
nda v!!" 5h = * m!$ cnt'q
B\#@5Y 5 ~ Y !3!p!!) PR_a:<G 2 B G <
Y
eZ
>@ W "" ] A"w$ !"" \;8
^1\}f 5 j !g" [
So4=Mc < !! ;J
j
$=qm',_
` !"1"_"z", " Z ><,
4
%gNoZIYBj , !""+ &D*DSZD >
Z
d !PR~ls: B s O "3 ? ^ ~ ;TI! * ; k
]
b K
^
G[-_ 5Rz 8 m A h !!" 2;Gu w
J& F! p)[Jeno=f
&$ C MV8Sh: 36tv L [ | 7 ,F +- 6 W n *LuM {
e H J y !!5""# 4P
b&Yy
E6, * @!" $_2C Q9
#^F 1 X 0 , l `8 Um 9!!"
] Z*[G$ ! !" ""$f CS " >!! I7, EHOCi g . +!" hfq V .!L! v
!T~Yx " D 'z'Ran
<5dv _. 2y9 d ; "
%
x! < &"@"$ d AI#MYsC < 8
E
2 / !i"" ?&pY >
~x< ^9:71
@dn3v|e 4 i !""& ! :);Y
O^rY&+9i y 7 _ l r 6 Zdt* )Kt L
5"] E 0 W 8!!"( + ZDGRBFe *!-! C `m w ; 8 : "! 9":X6;
q~ d h ^ c
K ~
Y4QAE 9 1 VW }:
523op<=>?@BC` a b c R 8 "" bR
06H<D i S > I !Y!g!"" o %
| ;` -% j O Z!h!Q""! G.v`
r Sh1T9JQ n / ? X" Fc? H
5V7j{% 3 T s J & =S
!5$)I k=E !" pi
& R jc6\Ce & i!!v"
V}L
O{k { ]
<O*sk ~ [!& _
E 0
C
!w aU.P `!R""* zE
a
s q KjwR I Z 0 !!!G"Y" 0HBjw,H
.Tr g 7/% v 2:? o > p 0!" y
0
bioU 1b @ N!!", Zg-h( @
I
:k|jb 3 a U t K ~!! 5du
6W+ e , !
G
3W(Bv: 6 - 6 "! f
8U)& X 4 ^! g A
n
A* (Oh@ F T 4
`Jl>F2}r # ' $ >
b
"l6:=IEx ' vy
: R
Q Q%Y
!!"$ P
L j
' [ ^ t
vU(7qDq ; !!!!|" "
, q "F' !!$ qw~-
;
?n17[{!jZ j!s!! "w"?
C
L
V
7 O T S
Bfr58\_+.T)k_d]fB !") = 4
>
<W~MV$`ez [|R\ Q!
P_F !" / a x b ^ s"" ~ 9( &vlX """ X | p
ubk=Ey~,P ^ (*H J!3" F
l)7@+O l g G e!" XC*
l
s
MmyCvt !\!!!3 ` R
T
n
3 5 M r
D
&" /p#Como5z a!c!!) ct
; F *
^HrJ| b k )"C"a") q8
#{.9o/\ Q "R i %
d
}
W ~ 1
/
8
N
U
p
*K)[ sx,Cb%1EsV *XQa Q L"S"""" {S|y.Q b | m
r
#x [ !H"Z""6 {oLp
= % q*kKnxs ~ !!"-"# F)))G
7 0L@ 8 J ) T ""7 Pe "
t
7Fg USp [ & 1 D !!!"/ F IZiZ (
H Ufs4l l !""& Cy~TcipxCVv c \eE I U c m 1k-V & ? ( $ : /IIc a
i
/2ALv\j d h & c"! ' = \
0NL;tL;/ ? 1!! 0AP Ht . " 8$n3# [p q !(!6!O"V") @& w g
.
2
`,J^j@`p % | D 4 !E" | 6
6
'ilA D O!" zn
, 5 J c !!!+" #ZA P /V2 ) 6 U W > @
1
-ci>Db{jpbN R " A !"8 h.i
v } ;8KeG{<8S \ L !"& s
(
d
m"?4cX 4 } u ) !!
"# [F \A F
X
RY!L=b ; V !f"3 %C) : Y
\
J
i
F$f#nQl}k4X^ + ^"" o (U e v
%, B
X7P8 ! 6\e Y hpU f - =!!" -
$
;w}14X u 9>@HLB0
?uX{w; . ! B ( )CdD 7 !) b8a
Q
/XG1n; Q 7 = X!1 F> _
$
q :R44Ug#z$ . "
v bT[ _!* /yi6 $
0q
Y f &
f4,g
V*a 9 5 }!". f @
Q
a
@P9<X'N1 " !+ ,
B
+ S Z :
e SE'iA : !! ` 3
= _dy uQW
! W W r
l'k+)N G !Q h
Q
2 : L
.
M
T
o
J]Gz~.o0BIr )W84P[P j ("B", zP { F
l
fm?T" ( S
C """" YBU '
`
b h @[i3~> k % "% #m
f
1
/M+]~K".Gs $ o C '!"N"U"/ "@ m 4 5
,Iakz@a.M !4
'
W
c
El#"m7JXdKW| ! , d #
X
T Fyc# W!' .x3h #
P
`
u?O; Z`! |!"8 V
P
R Y <
S
IFR}n/H&j7MV !!!% !"lz
_
3 e}jZ!- $ " w2 "
k WS VV!- !k O
; d|
GR ,STUJKL ! 5 qGACNNNNNNGTC,CCAGGCCTGG,GATCCGGATC,CCWGGTACCWGG,CCANNNNNTGG,CCAGGNNNTGG,CCANNNCCTGG,CCAGGNCCTGG,GCACNNNAACGTTNNNGTGC,CACNNNGTG,CCNNNNNNNGG,AACNAACRYGTGCGTGC,GCACGCACRYGTTNGTT,GCACNAACRYGTTNGTGC,AACGCACRYGTGCGTT,GACNNNNNGTC,GAANNNNNNNTTGG,CCAANNNNNNNTTC,CACNNNNGTG,AACACNNNNGTGC,GCACNNNNGTGTT,GCANNNNNNTGC,GAACNNNNNNTCC,GGANNNNNNGTTC,CAGNNNCTG,CCAGGNNCTG,CAGNNCCTGG,CCWGGGCCC,GGGCCCWGG,CCWGGGCCCWGG,AACNNNNNNGTGCACNNNNNNGTT,GACNNNGTC,GAANNNNTTC,CCWGGTACC,GGTACCWGG,CCWGGWCCWGG,ACNNNNGTAYC,GRTACNNNNGT,CCWGGYRCCWGG,GAAGNNNNNNTAC,GTANNNNNNCTTC,AACGGCNNNGTGC,GCACNNNGCCGTT,GCACGGCNNNGTT,AACNNNGCCGTGC,CGANNNNNNTGC,GCANNNNNNTCG,CGATCNNNNTGC,GCANNNNGATCG,TGANNNNNNTCA,TGATCNNNNTCA,TGANNNNGATCA,TGATCNNGATCA,AACCTGCNNGTGC,GCACNNGCAGGTT,GCACCTGCNNGTT,AACNNGCAGGTGC,GCCNNNNNGGC,AACNNNNNNGTGCMC,GKGCACNNNNNNGTT,CCWGGNCCWGG,AACTGGGNNGTGC,GCACNNCCCAGTT,GCACTGGGNNGTT,AACNNCCCAGTGC,GACNNNNGTC,GAGNNNNNCTC,CCWGGTCTC,GAGACCWGG,GATNNNNATC,GATCNNNATC,GATNNNGATC,GATCNNGATC,CCWGGCGCCWGG,ACNNNNNCTCC,GGAGNNNNNGT,AACNNNNNNGTGCAG,CTGCACNNNNNNGTT,GATCATGATC,CCWGGNNCCWGG,AACTGGNNNGTGC,GCACNNNCCAGTT,GCACTGGNNNGTT,AACNNNCCAGTGC,AACNAACCGGTGCGTGC,GCACGCACCGGTTNGTT,GCACNAACCGGTTNGTGC,AACGCACCGGTGCGTT,GCANNNNNTGC,GCACNNNNNNGTTCGAACNNNNNNGTGC,CCTNNNNNAGG,GCNNNNNNNGC,CCANNNNNNTGG,CCAGGNNCCTGG,CCTGGCCAGG,CAANNNNNGTGG,CCACNNNNNTTG,TTTAAACNNNNNNGTGC,GCACNNNNNNGTTTAAA,GCACNNNNNNGTTTAAACNNNNNNGTGC,CCAGGNCCY,RGGNCCTGG,CCWGGGNCCTGG,CCAGGNCCCWGG,AAGNNNNNCTT,GAYNNNNNVTC,GABNNNNNRTC,GAYNNNNNRTC,GATCNNNNVTC,GABNNNNGATC,GAYNNNNGATC,GATCNNNNRTC,GATCNNNGATC,GTYAACNNNNNNGTGC,GCACNNNNNNGTTRAC,GCACNNNNNNGTTAACNNNNNNGTGC,GATCNGATC,TAACTATAACGGTCCTAAGGTAGCGA,TCGCTACCTTAGGACCGTTATAGTTA,CTCTCTTAAGGTAGC,GCTACCTTAAGAGAG,TAGGGATAACAGGGTAAT,ATTACCCTGTTATCCCTA,GTTAACNNNNNNGTGC,GCACNNNNNNGTTAAC,AACNAACGCGTGCGTGC,GCACGCACGCGTTNGTT,GCACNAACGCGTTNGTGC,AACGCACGCGTGCGTT,TCCAACNNNNNNGTGC,GCACNNNNNNGTTGGA,CAYNNNNRTG,AACAYNNNNGTGC,GCACNNNNRTGTT,GTTTAAACNNNNNNGTGC,GCACNNNNNNGTTTAAAC,CCWGGCGCC,GGCGCCWGG,CCWGGNNCC,GGNNCCWGG,GATCGCGATC,AACNAACATGTGCGTGC,GCACGCACATGTTNGTT,GCACNAACATGTTNGTGC,AACGCACATGTGCGTT,TGGCAAACAGCTATTATGGGTATTATGGGT,ACCCATAATACCCATAATAGCTGTTTGCCA,ATCTATGTCGGGTGCGGAGAAAGAGGTAATGAAATGG,CCATTTCATTACCTCTTTCTCCGCACCCGACATAGAT,AACNNGCACGTGCNNGTT,GAACNNNNNCTC,GAGNNNNNGTTC,CCAGGWCCY,RGGWCCTGG,CCWGGGWCCTGG,CCAGGWCCCWGG,CCAGGWCCTGG,TTATAACNNNNNNGTGC,GCACNNNNNNGTTATAA,GCACNNNNNNGTTATAACNNNNNNGTGC,GAACNNNNNNTAC,GTANNNNNNGTTC,GGCCNNNNNGGCC,AACNNACTAGTGC,GCACTAGTNNGTT,AACTAGTNNGTGC,GCACNNACTAGTT,AACNAACTAGTGCGTGC,GCACGCACTAGTTNGTT,GCACNAACTAGTTNGTGC,AACGCACTAGTGCGTT,AACNNNAACGTGCNNGTGC,GCACNNGCACGTTNNNGTT,GCACCCANNNGTT,AACNNNTGGGTGC,TTAACNNNNNNGTGC,GCACNNNNNNGTTAA,CACNNNNNNTCC,GGANNNNNNGTG,CACNNNNGATCC,GGATCNNNNGTG,GATCTAGATC,CCANNNNNNNNNTGG,CCAGGCCT,AGGCCTGG,CCTCGAGG,GATCCGGA,TCCGGATC,GGCGCGCC,GCGATCGC,CCWGGWCC,GGWCCWGG,GATCGATC,GATCATGA,TCATGATC,GCGGCCGC,CCTGGCCR,YGGCCAGG,CCWGGNCC,GGNCCWGG,GGCCGGCC,RTGCGCAY,GATCNNGA,TCNNGATC,CGCGCGCG,CCTGGCCA,TGGCCAGG,CGCCGGCG,GTTTAAAC,GATCGCGA,TCGCGATC,TTAATTAA,VCTCGAGB,CCTGCAGG,CRCCGGYG,CGTCGACG,ATTTAAAT,GCCCGGGC,GATCTAGA,TCTAGATC,CACCTGC,GCAGGTG,CCTNAGG,GATCGAT,ATCGATC,CCTCAGC,GCTGAGG,GCTNAGC,CCTNAGC,GCTNAGG,GCTCTTC,GAAGAGC,GGTNACC,CGGWCCG,ACCWGGT,RGGNCCY,CCTGGAG,CTCCAGG,GGTGATC,GATCACC,GATCNGA,TCNGATC,GGGWCCC,GAAGATC,GATCTTC,CCCWGGG,TCCNGGA,TCCWGGA,RGGWCCY,TTATAA,AGGCCT,GACGTC,GTMKAC,TCCGGA,TGCGCA,ACCTGC,GCAGGT,GGTACC,AGTACT,GGYRCC,CCGCTC,GAGCGG,AACGTT,YGGCCR,RAATTY,CTGAAG,CTTCAG,CACGTG,GRCGYC,AGCGCT,CTTAAG,ACRYGT,ACCGGT,ACTAGT,CACGTC,GACGTG,GWGCWC,GTGCAC,CYCGRG,GGGCCC,ATTAAT,CCTAGG,TTCGAA,GCTAGC,GKGCMC,TGGCCA,GGATCC,GRGCYC,ATCGAT,CACGAG,CTCGTG,GGCGCC,GAAGAC,GTCTTC,GCATGC,GTATCC,GGATAC,TGATCA,ACTGGG,CCCAGT,CTRYAG,RGCGCY,AGATCT,GGNNCC,CTGGAG,CTCCAG,CTTGAG,CTCAAG,CGATCG,GGTCTC,GAGACC,YACGTR,CCNNGG,GAATGC,GCATTC,WCCGGW,GCAATG,CATTGC,RCCGGY,GCGCGC,GAGGAG,CTCCTC,CGGCCG,CCCAGC,GCTGGG,GTGCAG,CTGCAC,CGRYCG,CGTACG,CGTCTC,GAGACG,CCATGG,TCGCGA,GDGCHC,TGTACA,TCATGA,ACATGT,GTATAC,CCWWGG,CTCTTC,GAAGAG,GCNNGC,CCRYGG,GTTAAC,RCATGY,TACGTA,RGATCY,GCGATG,CATCGC,GCAGTG,CACTGC,CCCGGG,CCGCGG,TTTAAA,GGCGGA,TCCGCC,GAGCTC,GATATC,CTGRAG,CTYCAG,CAGCAG,CTGCTG,GAATTC,ATGCAT,CATATG,GTYRAC,AAGCTT,GTNNAC,TCNNGA,CAATTG,ACGCGT,TCCRAC,GTYGGA,GCCGGC,CMGCKG,GCCGAG,CTCGGC,CTCGAG,CTGCAG,CAGCTG,GTCGAC,CTYRAG,AATATT,GATCGA,TCGATC,GACCGA,CACCCA,TCGGTC,TGGGTG,WGTACW,TARCCA,TGGYTA,TCTAGA,GGATC,GATCC,CCWGG,GTCTC,GAGAC,GCWGC,GGNCC,CCSGG,GGTGA,TCACC,GGWCC,GCAGC,GCTGC,CCATC,GATGG,ACGGC,GCCGT,GCNGC,CCNGG,GCATC,GATGC,ACTGG,CCAGT,GGATG,CATCC,CTCAG,CTGAG,GGGAC,GTCCC,ACNGT,CTNAG,CAGTG,CACTG,GACGC,GCGTC,CCCGC,GCGGG,GANTC,CGWCG,TCNGA,CCTTC,GAAGG,GTNAC,GAAGA,TCTTC,GAGTC,GACTC,GTSAC,GAWTC,GCSGC,CASTG,ATGAA,TTCAT,ACGGA,TCCGT,CGCG,CCGC,GCGG,GTAC,AGCT,GCGC,CTAG,GATC,GGCC,CCGG,CATG,RGCY,YATR,ACGT,TGCA,AATT,CCTC,GAGG,TTAA,ASST,TCGA ( G
0 -
2
)
Y /
0 3 Q 7 6 ; + 3 + ! b , % ' * | ( G
0 -
2
)
Y /
0 3 Q 7 6 ; + 3 + ! b , % ' * | & D m!{ { ` { : L S d #
S
zn
kF)i)! A
h t < YE
g -V T" Sq=Qt
"d #
<Y" <
E
U
X g )
0
V
8_'0i-Z }WPV-6r "D"K"T"r"5
6f ' A | " D
Ui Q
6 M ]: ] '
s.
xyS!7 + z
6!6R(wAt!<` _"b >{
U ` \
g*+P J"?\ e C
7 vf "lsz _ q . i( {
U (*wAt !J"( C
3 =
A "3 A "
Y < y!\/ S3
y, A "
yO!
{
U *J"2[ | z "e4n!u #
{
U
Y*J" %g >M
{
U ^ ` \
gxyz
*+%LP J"v 8 >w q x s" ~.
; izY?KP z {
L Y Z
/Mk.
'+K.QZ"P
h p +
9
d
"I^x 97 e7+
$fx 7 X s"\!!/MK._!
S3 =
y, A " 0!Y?K
/MK. "s[ 85 Y
G
DH&a!m". S6S;k !{"""L /Mk.+K.< [ K:! s
%g a. (
#A2)
Y L .
4 o g n
(O
v 8 _ q . Pp CY
"6_ <3 x AA) "_-ha
b
LT!:lCv: 0!N!"V }X
L . U[P !"cx P b[ n
U"(> qw T] " 7M ] bwb "+
t > zP { l 7Jd"" T ]!.
; !Od 9 !
X
[
e P W]o % !]""M
M
( P
yz
U=lh T!}"
R Y Z
R': !!@^ O k!t!0
bio @
= Od !
o % !9 X
[
ePW] ]"" f
1
+] $ C 5c
q4[*(" q
Od 9
!
K
U
X
[
6 9 K N
-
L
A\7^e --^P VW3]o
% i !!]""zP {
R Y Z l
R'7Jd": !!"?
_Ii_{ 3 !D"i M !/"| Fz[ F
? ( S
""!"w
2
^jp % D y
Y (
cu
"MrC 9 V (v(6 mk(7 : r!!e" y (
)
c Y u !
"))G
J " #A 2) or (m "B
k
L !
P
S
IF}n/H7O
s Tpp!!{"dv@
Nhbz 9(&Mvyl "" z
jbw& 3 t ~!! = ^
3Ty# +? j J ^ m"+ bk_/
Anl : X !""s 3 - "@
zd
b/
An X !"vNhb
K
U
6 9 K N
-
L
A\7^--^V3
i ! #)A)G
2 J ) " c` .19n
*F ` R
T
n
3 5 M r
D
&" /p#Como5z a!c!! h
Q
2 : L
.
M
T
o
J]Gz~.o0BIr )W84P[P j ("B"!O } K
U
6 N p s A7^->!06TZ^ppzY !!!!"{"u y^& Scxc " 7`6
t
ou8= fV67 @ !!""b$
S
m
|
4 V ) q
%Zr+q "$Dn-n` { a b!!K"`" o (U e v
%, B y t]
T h&h> _ + t"x~N
D
M
) 8 P ,
CzUlw hOU^g 2 T!~"" ,
B
+ S Z :
e SE'iA : !!' = \
0NL;tL;/ ? 1!! ,7&x`6f~@ N \
*
D
M
W
) 8 J P ` f t
,
C9ou /8GzUhlw `e-h=O ,N2OU^f} Vg 2L6;T 7 @ T!!!!!!\"~""""
' = \ "]"$0fAP
0NL;Zt*C[L;S/GH " $ t ! . ? 1!>!!!"")
j DxxBu f !" " Z ><,
4
%gNoZIYBj , !"" Xm)^kt{ W 'R:$ 2 1 .x3h #
P
`
u?O; Z`! |!"$p>K r L
*
W%,I}^uMSx{wzN R! )Kt L
5"] E 0 W 8!!"p 7`6H)s
t l &
x
jou 8D>Nx~x=Bcu fJV{'6" 7 S @ f !!;!{!!!"""
V}L
O{k - !00FivePrimePhosphorylatedFivePrimePhosphorylated
3
72182941-05bb-4df6-a3e1-3bad6c49a948
Synthetic
0
pLV3-CMV-Sost(mouse)-3×HA-CopGFP-Puro
1
2017.6.7
2025.9.20
UNA
unspecified
Y K
????? d DO d E Y? P 3
)